[PDF][PDF] Bone markers

D Konukoglu - Int J Med Biochem, 2019 - jag.journalagent.com
… tropocollagen are the Ntelopeptide and C-telopeptide regions. Cross-links … that monoclonal
antibodies against sclerostin decrease bone resorption … Serum CTX is always ß-isomerized. …

Bone turnover markers: basic biology to clinical applications

M Schini, T Vilaca, F Gossiel, S Salam… - Endocrine …, 2023 - academic.oup.com
… In the last 20 years, much experience has been gained in measurement and … used resorption
markers (serum C-telopeptides of type I collagen, urinary N-telopeptides of type I collagen, …

… ) as a Sampling Technique for β Isomerized Carboxy Terminal Telopeptide (β-CTX) and Type 1 Procollagen Amino Terminal Propeptide (P1NP) Determination Using …

C Washbourne - 2022 - ueaeprints.uea.ac.uk
… on the collagen formation and breakdown products 83 for this … and 325 providing the
reaction environment with the co-… using two monoclonal antibodies against the linear β‑8 342 …

Current use of bone turnover markers in the management of osteoporosis

JP Brown, A Don-Wauchope, P Douville, C Albert… - Clinical …, 2022 - Elsevier
… of bone collagen molecules (N- [NTX] and C-telopeptide … assays using of two antibodies to
the same amino acid sequence … β isomerization occurs in bone tissue in vivo with aging and is …

Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood

HP Bhattoa, E Cavalier, R Eastell, AC Heijboer… - Clinica Chimica …, 2021 - Elsevier
… and released during bone formation, and the C-telopeptide (β-… The anti-PINP antibodies
recognize two molecular forms of … available assays for the measurement of serum PINP. Table 1 …

Advances in bone turnover markers

L Di Medio, ML Brandi - Advances in Clinical Chemistry, 2021 - Elsevier
… -linking region in the C-telopeptide region is the carboxy-… from the newly synthesized form
(αCTX) to an isomerized form (βCTX). … antibodies directed against sclerostin decreased bone

Biomarkers of Bone Remodeling

F Pagani, M Zaninotto - Clinical and Laboratory Medicine Textbook, 2024 - Springer
… the measurement of CTX, these methods use antibodies specific for the octapeptide containing
a β-isomerized aspartic acid … of urinary degradation products derived from type I collagen. …

Bone Turnover Markers

S Ichimura - Osteoporotic Fracture and Systemic Skeletal Disorders …, 2021 - Springer
… cross-linked C-telopeptide (CTX), and type I collagen cross-… is similarly measured using an
antibody against the 8-residue … Identification of aβ–isomerized Asp-Gly sequence with the C-…

Soluble biological markers in osteoarthritis

JC Rousseau, R Chapurlat… - Therapeutic Advances in …, 2021 - journals.sagepub.com
products (AGEs) such as pentosidine and the isomerization … -II antibody recognizes the
human type III collagen sequence … stress and structural degradation products. Significant sex-…

[HTML][HTML] Utility of bone turnover markers in metabolic bone diseases

J Aggarwal, M Modi, RN Gupta… - … University Journal of …, 2023 - journals.lww.com
… [ 13 , 14 ] There are two monoclonal antibodies which are utilized by … , nonisomerized (αCTX)
and isomerized (αCTX) form. … assays to measure the CTX (C-telopeptide of type I collagen), …